Cardiac and Vascular

Mesenchymal Precursor Cells Reduce Mortality and Major Morbidity in Ischaemic Heart Failure with Inflammation: DREAM-HF – European Journal of Heart Failure, November 2024

Phase 3 DREAM-HF Trial of Mesenchymal Precursor Cells in Chronic Heart Failure; A Review of Biological Plausibility and Implementation of Flexible Clinical Trial Design – Circulation Research, July 2019

A Phase II Dose-Escalation Study of Allogeneic Mesenchymal Precursor Cells in Patients With Ischemic or Nonischemic Heart Failure – Circulation Research, July 2015

Mesenchymal Precursor Cells as Adjunctive Therapy in Recipients of Contemporary Left Ventricular Assist Devices – Circulation, June 2014

Intracoronary Infusion of Allogeneic Mesenchymal Precursor Cells Directly Following Experimental Acute Myocardial Infarction Reduces Infarct Size, Abrogates Adverse Remodeling and Improves Cardiac Function – Circulation Research, May 2013

Catheter-Based Endomyocardial Delivery of Mesenchymal Precursor Cells Using 3D Echo Guidance Improves Cardiac Function in a Chronic Myocardial Injury Ovine Model – Cell Transplant, September 2012

Therapeutic Effects of Human STRO-3-Selected Mesenchymal Precursor Cells and their Soluble Factors in Experimental Myocardial Ischemia – Journal of Cellular and Molecular Medicine, November 2010

Reparative Effects of Allogeneic Mesenchymal Precursor Cells Delivered Transendocardially in Experimental Nonischemic Cardiomyopathy – JACC: Cardiovascular Interventions, September 2010

Enrichment for STRO-1 Expression Enhances the Cardiovascular Paracrine Activity of Human Bone Marrow-Derived Mesenchymal Cell Populations – Journal of Cellular Physiology, May 2010

A Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Study of Intravenous Adult Human Mesenchymal Stem Cells (Prochymal) After Acute Myocardial Infarction – Journal of the American College of Cardiology, December 2009

Mesenchymal Cell Transplantation and Myocardial Remodeling After Myocardial Infarction – Circulation, 1 October 2009

Allogeneic Mesenchymal Precursor Cell Therapy to Limit Remodeling After Myocardial Infarction: The Effect of Cell Dosage – Annals of Thoracic Surgery, March 2009

Mesenchymal lineage precursor cells induce vascular network formation in ischemic myocardium – Nature, March 2006